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Semaglutide (GLP-1) 2mg

$84.00

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Product Usage: This PRODUCTS ARE INTENDED FOR RESEARCH CHEMICAL ONLY. This designation allows the use of research chemicals strictly for in vitro testing and laboratory experimentation only. All product information available on this website is for educational purposes only. Bodily introduction of any kind into humans or animals is strictly forbidden by law. This product should only be handled by licensed, qualified professionals. This product is not a drug, food, or cosmetic and may not be misbranded, misused, or mislabeled as a drug, food, or cosmetic.

Description

Semaglutide, a GLP-1 receptor agonist, effectively lowers blood glucose levels, promotes significant weight loss, reduces major cardiovascular events, decreases postprandial inflammation (PMID: 32910488, PMID: 32910487, PMID: 33068776 ).

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`GLP-1 receptor agonist Semaglutide Research Topics:

  1. Glycemic Control:

    Semaglutide significantly lowers blood glucose levels in individuals with type 2 diabetes by stimulating insulin secretion, suppressing glucagon release, and slowing gastric emptying (PMID: 32910488, PMID: 32910487).
  2. Weight Loss:

    It promotes substantial weight loss by reducing appetite and increasing feelings of fullness, which helps in the management of obesity (PMID: 32910488, PMID: 32910487).
  3. Cardiovascular Benefits:

    Semaglutide reduces the risk of major adverse cardiovascular events, including heart attack and stroke, making it beneficial for patients with type 2 diabetes at high cardiovascular risk (PMID: 32910488, PMID: 33068776).
  4. Anti-Inflammatory Effects:

    It decreases postprandial inflammation markers such as IL-6, which contributes to better overall metabolic health (PMID: 32910488).

Related Research

The differences in weight loss percentages for GLP-1 (Semaglutide), GLP-1/GIP (Tirzepatide), and GLP-1/GIP/GCGR (Retatrutide) are as follows:

  1. Semaglutide (GLP-1):

    In clinical trials, Semaglutide resulted in a weight loss of approximately 12% over a period of 68 weeks (PMID: 32910488).
  2. Tirzepatide (GLP-1/GIP):

    Tirzepatide demonstrated a weight loss ranging from 15% to 21% in different studies over a period of 72 weeks (PMID: 32910487).
  3. Retatrutide (GLP-1/GIP/GCGR):

    In a phase 2 trial, Retatrutide showed a placebo-subtracted weight loss ranging from 6.6% to 22.1% over 48 weeks (PMID: 37366315).

 

Peer-Reviewed Studies 

Wilding, J. P., Batterham, R. L., Calanna, S., Davies, M., Van Gaal, L. F., Lingvay, I., … & Kushner, R. F. (2021). New England Journal of Medicine.

Marso, S. P., Bain, S. C., Consoli, A., Eliaschewitz, F. G., Jódar, E., Leiter, L. A., … & Vilsbøll, T. (2016). N Engl J Med375, 1834-1844.

Structure

Sequence: HXEGTFTSDVSSYLEGQAAK­
OH.steric diacid-EFIAWLVRGRG
Molecular Formula: C187H291N45O59 Molecular Weight: 4113.64 g/mol
PubChem CID: 56843331
CAS Number: 910463-68-2
Synonyms: Semaglutide, Oxempic, Rybelsus, NN9535

Weight 0.05 kg
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