TB-500 (Thymosin Beta-4) Research Topics:
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Tissue Repair and Wound Healing:
TB-500 accelerates the repair of injured tissues by promoting cell migration, differentiation, and new blood vessel formation. This peptide significantly enhances wound healing and reduces scarring. (PMID: 38382158) -
Cardiovascular Health:
TB-500 has been shown to improve cardiac function by reducing inflammation and promoting angiogenesis (the formation of new blood vessels). It can help mediate cardioprotection, especially following myocardial infarction. (PMID: 17495252) -
Reduction of Inflammation:
The peptide has potent anti-inflammatory properties, making it useful for reducing inflammation in various tissues, including the cardiovascular system. (PMID: 34280397) -
Hair Growth:
TB-500 has been observed to aid in hair growth by promoting cell proliferation and angiogenesis, which improves nutrient delivery to hair follicles. (PMID: 27130465)
Peer-Reviewed Studies
- Synthesis and characterization of the N‐terminal acetylated 17‐23 fragment of thymosin beta 4 identified in TB‐500, a product suspected to possess doping potential Esposito, S., Deventer, K., Goeman, J., Van der Eycken, J., & Van Eenoo, P. (2012)Drug testing and analysis, 4(9), 733-738.
- Adsorption effects of the doping relevant peptides Insulin Lispro, Synachten, TB-500 and GHRP 5 Judák, P., Van Eenoo, P., & Deventer, K. (2017) Analytical biochemistry, 537, 69-71.
Structure
Sequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glulle-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-ThrGlu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-GluThr-lle-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser Molecular formula: C212H350N5s01aS
Molar Mass: 4963.4408
CAS number: 77591-33-4
PubChem: CID 16132341