SS-31 Research Topics:
-
Mitochondrial Protection:
SS-31 targets and stabilizes mitochondrial membranes, reducing oxidative stress and improving mitochondrial function. This action helps to prevent cell death and reduce inflammation, particularly beneficial for conditions like ischemia-reperfusion injury and chronic kidney disease (PMID: 31747905).
-
Cardiovascular Health:
By protecting mitochondria in cardiac cells, SS-31 can reduce the severity of myocardial ischemia-reperfusion injury, thus enhancing heart health and function (PMID: 32779818).
-
Neuroprotection and Cognitive Benefits:
SS-31 improves cognitive function and memory by reducing oxidative damage in the brain, potentially aiding in the treatment of neurodegenerative diseases like Alzheimer’s (PMID: 31747905).
-
Muscle Performance and Recovery:
The peptide enhances exercise endurance and muscle recovery by improving mitochondrial efficiency and reducing muscle fatigue, which can be particularly beneficial for aging populations and athletes (PMID: 34461564).
Structure
Sequence: D-Arg-Tyr(2,6-diMe)-Lys-Phe Molecular Formula: C32H49N905
Molecular Weight: 639.8 g/mol
PubChem CID: 11764719
CAS Number: 736992-21-5
Synonyms: elamipretide, MTP-131, Bendavia
Source: PubChem