Description
Structure & Identity
BPC-157 is a pentadecapeptide, a chain of fifteen amino acids with the sequence Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val. It is a partial sequence derived from a larger gastric protein, and it is notably stable, holding up in conditions that would break down many peptides. That stability is a practical advantage in the lab.
Research Background
BPC-157 research spans gastric-cell signaling, cytoprotection signaling, and blood-vessel (angiogenesis) signaling.
- Gastric origin. BPC-157 is a partial sequence of a protective protein found in gastric juice, and it is notably stable [PMID: 30915550].
- Gastrointestinal models. It was studied early in gastric-cell and GI-signaling contexts, including the related PL-14736 [PMID: 17186181].
- Cytoprotection signaling. Reviews describe its role in cytoprotection and growth-factor signaling across research models [PMID: 30915550].
- Angiogenesis. Recent work examined its relation to blood-vessel formation and nitric-oxide signaling [PMID: 41155565].
- Gastric-cell models. It has been studied in drug-challenged gastric-cell models in rats [PMID: 33376304].
These are research contexts, not approved uses, and the peptide is intended purely for laboratory study.
Specifications
| Attribute | Value |
| Chemical name | BPC-157 (body protection compound-157) |
| Also Known As | Body Protection Compound 157, PL-14736 (related) |
| Sequence | Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val |
| CAS number | 137525-51-0 |
| Molecular formula | C62H98N16O22 |
| Molecular weight | 1419.5 g/mol |
| Purity | ≥99% by reverse-phase HPLC |
| Length | 15 amino acids |
| Identity | Confirmed by ESI mass spectrometry |
| Physical form | Lyophilized powder |
| Appearance | White to off-white solid |
| Quantity | 10 mg per vial |
| Storage | -20°C, protected from light |
| Solubility | Soluble in bacteriostatic or sterile water |
| Classification | Research use only |
Storage & Handling
Keep the sealed vial frozen at -20°C and shielded from light until use. After preparing, store the solution at 2-8°C and use it in your research within about two weeks. BPC-157 is relatively stable for a peptide, but warming the vial to room temperature before opening and avoiding repeated freeze-thaw cycles are still worthwhile habits that protect the material.
Quality Assurance
BPC-157 is produced under research-grade manufacturing controls and released only after an outside lab has verified it. Purity is measured by reverse-phase HPLC and identity by mass spectrometry, with that testing carried out by independent third-party laboratories, including Janoshik Analytical and domestic US labs. A certificate of analysis is issued for each batch, so its figures match the exact vial you receive.
Frequently Asked Questions
What is BPC-157?
BPC-157 is a synthetic 15-amino-acid peptide derived from a protein in gastric juice. It is studied in angiogenesis and gastrointestinal research and is supplied for research use only.
What does “BPC” stand for?
Body Protection Compound. The name reflects the gastric protein the peptide’s sequence comes from, which is the origin of most of its research interest.
Why is BPC-157 considered stable?
It resists breakdown better than many peptides, holding up in conditions that would degrade others. That stability makes it convenient to handle and study in the lab.
Is BPC-157 FDA approved?
No. BPC-157 is not FDA approved. In 2026 an FDA advisory committee recommended it for a compounding list, but that is not an approval. The material here is a research-use-only reference peptide, not for human or veterinary use.
What is BPC-157’s sequence and molecular weight?
Its sequence is Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, its formula is C62H98N16O22, and its molecular weight is about 1419.5 g/mol, with CAS number 137525-51-0.
How is BPC-157 different from TB-500?
They are studied across overlapping pathways but are different molecules, BPC-157 around angiogenesis and TB-500 around actin and cell migration.
How should BPC-157 be stored?
Keep the powder frozen at -20°C and protected from light. Once reconstituted for research, store the solution at 2-8°C and use within about two weeks.
How is this BPC-157 verified?
It is tested to ≥99% purity by reverse-phase HPLC with mass-spec identity confirmation by an independent lab, and each batch ships with its own certificate of analysis.
