CAS: 53-84-9 · MW: 663.43 Da · Purity: ≥99% by reverse-phase HPLC · Format: 500 mg powder · Identity: ESI-MS confirmed
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme, not a peptide. It is one of the most important helper molecules in the cell, carrying electrons in the reactions that produce energy and acting as a fuel for a family of enzymes tied to aging and metabolism. This is a 500 mg vial, supplied for metabolic and cellular-energy research.
Structure & Identity
NAD+ is a dinucleotide, built from two nucleotides, one carrying nicotinamide and one carrying adenine, joined through their phosphate groups. It is a coenzyme with the molecular formula C₂₁H₂₇N₇O₁₄P₂ and a molecular weight of 663.43 Da. Because it contains no amino-acid chain, it is not a peptide, despite where the product slug might suggest otherwise.
Research Background
NAD+ research is central to cellular energy and the enzymes that depend on it.
- Central coenzyme. NAD+ carries electrons in the reactions that produce cellular energy [PMID: 32694684].
- Homeostasis. How cells maintain NAD+ is a core research question in health and disease [PMID: 32694684].
- Sirtuin fuel. NAD+ fuels sirtuin enzymes; the NAD+/sirtuin pathway is studied for longevity [PMID: 23870130].
- Energy regulation. It links to AMPK and SIRT1 in energy-expenditure research [PMID: 19262508].
- Broader signaling. The wider sirtuin network ties NAD+ to metabolism and mitochondria [PMID: 42442718].
These are research contexts, not approved uses, and the compound is intended for laboratory study.
Specifications
| Attribute |
Value |
| Chemical name |
NAD+ (nicotinamide adenine dinucleotide) |
| Type |
Coenzyme (dinucleotide), not a peptide |
| Also Known As |
Nicotinamide adenine dinucleotide |
| CAS number |
53-84-9 |
| Molecular formula |
C₂₁H₂₇N₇O₁₄P₂ |
| Molecular weight |
663.43 g/mol |
| Purity |
≥99% by reverse-phase HPLC |
| Identity |
Confirmed by ESI mass spectrometry |
| Physical form |
Lyophilized powder |
| Appearance |
White to off-white solid |
| Quantity |
500 mg per vial |
| Storage |
-20°C, protected from light |
| Solubility |
Freely water-soluble |
| Classification |
Research use only |
Storage & Handling
Keep the sealed vial frozen at -20°C and shielded from light until use. NAD+ is sensitive to moisture and heat, so let the vial reach room temperature before opening, reseal promptly, and keep reconstituted solution cold and reasonably fresh. Avoid repeated freeze-thaw cycles.
Storage and Handling Guide
Quality Assurance
NAD+ is produced to research-grade standards and verified by an independent lab before release. Purity is measured by reverse-phase HPLC and identity by mass spectrometry, with testing carried out by third-party laboratories, including Janoshik Analytical and domestic labs. A certificate of analysis is issued for each batch, so its figures match the exact vial you receive.
Quality & Testing
Frequently Asked Questions
Is NAD+ a peptide?
No. NAD+ is a coenzyme (a dinucleotide), not a peptide. It contains no amino-acid chain. It is studied in metabolism and cellular-energy research and is supplied for research use only.
What does NAD+ do in the cell?
It carries electrons in the reactions that generate energy and serves as a substrate for sirtuin enzymes. That dual role makes it central to metabolism and aging research.
What are sirtuins, and how do they relate to NAD+?
Sirtuins are enzymes involved in metabolism and aging that use NAD+ as a fuel. The NAD+/sirtuin pathway is one of the most-studied areas in NAD+ research.
What is NAD+’s molecular weight?
Its formula is C₂₁H₂₇N₇O₁₄P₂, its molecular weight is 663.43 Da, and its CAS number is 53-84-9.
Is NAD+ FDA approved?
The material sold here is a research-use-only reference compound, not for human or veterinary use, diagnosis, or treatment.
Why does the product name include “peptide”?
The URL slug uses that word, but NAD+ is not a peptide. The correct description is a coenzyme, and the page reflects that.
How should NAD+ be stored?
Keep the powder frozen at -20°C and protected from light, reseal promptly after opening, and keep it away from heat and moisture.
How is this NAD+ verified?
It is tested to ≥99% purity by reverse-phase HPLC with mass-spec identity confirmation by an independent lab, and each batch ships with a certificate of analysis.
References
- NAD+ homeostasis in health and disease. 2020. PMID: 32694684.
- The NAD+/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial function. 2013. PMID: 23870130.
- AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity. 2009. PMID: 19262508.
