Last updated: June 2026. 2025–2026 was an extinction-level stretch for grey-market research-peptide suppliers. At least eight major vendors went dark between mid-2025 and early 2026 under a convergence of FDA enforcement, pharmaceutical litigation against GLP-1 suppliers, payment-processor cutoffs, and failed third-party testing. The real question now isn’t “where’s the cheapest replacement” — it’s “how do I tell who is actually trustworthy before I send money again.”

This page is two things: a sourced status list of who closed and who is still operating, and a 7-point checklist you can apply to any vendor yourself. We operate Life Link Research, so treat our self-assessment with appropriate skepticism — every claim we make about ourselves links to verifiable proof, and the checklist lets you score us exactly the way you would score anyone else. For licensed laboratory research use only.

The shutdown list (2025–2026)

Status reflects publicly reported cessation of operations; verify current status before transacting with anyone.

VendorStatusWhenPublicly reported reason
Peptide SciencesClosedMar 6, 2026Voluntary shutdown amid FDA pressure, GLP-1 litigation, and failed third-party retatrutide testing
Science.bioClosedJan 2026Ceased operations under regulatory pressure
Amino AsylumClosed2025FDA warehouse raid (June 2025); founders entered federal guilty pleas (Dec 2025)
Paradigm PeptidesClosed2025–2026Reported closure during the enforcement wave
Royal ResearchClosed2025–2026Reported closure during the enforcement wave
Peptide Tech LabsClosed2025–2026Reported closure during the enforcement wave
American Research LabsClosed2025–2026Reported closure during the enforcement wave
Unchained CompoundsClosed2025–2026Reported closure during the enforcement wave

Deep-dives: What happened to Peptide Sciences, Science.bio, Amino Asylum, Paradigm Peptides.

What caused the 2025–2026 vendor collapse

  1. FDA enforcement escalated from letters to raids — 50+ warning letters to GLP-1 compounders and manufacturers in September 2025, plus at least one warehouse raid that took a major vendor offline overnight.
  2. GLP-1 litigation from Eli Lilly and Novo Nordisk targeting retatrutide, tirzepatide, and semaglutide suppliers.
  3. Payment-processor cutoffs that stranded orders.
  4. Failed third-party testing — independent labs flagged quality failures (e.g., retatrutide failing across dozens of samples at one major vendor), the trust trigger that pushed buyers to leave.

The 7-point vendor trust checklist (score anyone, including us)

Give 1 point per “yes.” 6–7 = strong; 4–5 = proceed with caution; 3 or fewer = walk away.

  1. Third-party COA, not in-house — a certificate of analysis from an independent lab (e.g., Janoshik), not a self-issued sheet.
  2. Batch/lot-specific COAs — the lot number on the COA matches the vial you receive.
  3. Full panel — identity and purity, plus sterility, endotoxin, heavy-metals, and residual-solvents for injectables.
  4. Public COA library — browsable on-site before you buy.
  5. Track record — 12+ months under the same name with a real support channel.
  6. Domestic stock & fulfillment — US warehouse and shipping.
  7. Transparent ownership & stable payments.

How Life Link Research scores (verify it yourself)

CriterionLife LinkProof
Third-party COAYesJanoshik & third-party labs — COA library
Batch/lot-specificYesLot numbers shown on COAs
Full 6-test panelYesIdentity, purity, solvents, metals, endotoxin, sterility
Public COA libraryYeslifelinkresearch.com/coa
Track recordYesOperating with responsive support
US stock & shippingYesShips from the USA
Transparent + stable paymentsYesCard, ACH, and BTCPay crypto; 30-day money-back guarantee

Don’t take our word for it — open the COA library, pick a product, and check the lot number against what ships.

If your vendor shut down, here is the tested equivalent

Mapped to the closed vendors’ most-popular compounds (GLP-1 analogs first). For licensed laboratory research use only.

If you bought…From a closed vendorTested equivalent at Life Link
RetatrutidePeptide SciencesBrowse retatrutide
TirzepatidePeptide Sciences / ParadigmBrowse tirzepatide
SemaglutideMultipleBrowse semaglutide
Cagrisema / CagrilintideMultipleBrowse cagrisema
BPC-157 / TB-500Amino Asylum / Science.bioBrowse BPC-157
Ipamorelin / CJC-1295 / GHK-Cu / KPV / DSIP / MT-2Science.bio / Amino AsylumShop all

Switching from a closed vendor? Use code SWITCH15 for 15% off your first order.

Frequently asked questions

Which research peptide vendors shut down in 2026?

Peptide Sciences (March 6, 2026) and Science.bio (January 2026) are the largest; at least eight closed across 2025–2026, including Amino Asylum, Paradigm Peptides, Royal Research, Peptide Tech Labs, American Research Labs, and Unchained Compounds.

Why did so many peptide vendors close at once?

A convergence of FDA enforcement (warning letters and at least one warehouse raid), GLP-1 litigation from Eli Lilly and Novo Nordisk, payment-processor cutoffs, and failed third-party testing.

How do I know if a peptide vendor is legit?

Apply the 7-point checklist above. The single most important factors are independent, batch-specific COAs and a public COA library you can check before buying.

What is a trustworthy alternative now?

Any vendor that scores 6–7 on the checklist. We score our own COAs and testing transparently above so you can verify rather than trust.


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