Description

KPV (Lysine-Proline-Valine) Research Topics:

1. 1. Anti-inflammatory Effects:

      KPV significantly reduces inflammation by interacting directly with inflammatory signaling molecules. This makes it effective in treating conditions like colitis, asthma, and other inflammatory diseases. It reduces pro-inflammatory cytokine levels and helps manage inflammation in immune and epithelial cells. (PMID: 28143741)​

   2. Supports Immune Function:

      KPV enhances the immune system by stimulating the production of immune cells and reducing pro-inflammatory cytokines. This helps in managing conditions like inflammatory bowel disease (IBD) and colitis, and in lowering the body’s inflammatory response. (PMID: 28143741)​

   3. Wound Healing:

      The peptide accelerates wound healing by reducing inflammation, fighting infection, and modulating collagen metabolism. This leads to improved cosmetic outcomes, such as smaller and less prominent scars, and prevents hypertrophic scars and keloids.​ (PMID: 28143741)​

   4. Antimicrobial Properties:

      KPV exhibits strong antimicrobial effects against pathogens like Staphylococcus aureus and Candida albicans. This makes it beneficial for treating infections and preventing microbial colonization in wounds. (PMID: 28143741)​

   5. Gut Health:

      KPV helps in healing the gut by reducing inflammation and repairing the mucosal barrier. It is effective in treating IBD and other gastrointestinal issues, promoting overall gut health.​ (PMID: 28143741)​

   6. Potential Cancer Benefits:

      Preliminary studies suggest that KPV can reduce tumorigenesis and inflammation associated with cancer, particularly in colon cancer, by inhibiting pro-inflammatory pathways. (PMID: 28143741)​

   7. Skin Health:

      KPV is effective in treating skin conditions like eczema and psoriasis by reducing inflammation and promoting healing. It also has anti-allergenic properties that help manage allergic skin reactions.​ (PMID: 28143741)​

Structure

Amino Acid Sequence: Lys-Pro-Val
Molecular Formula: C16H30N404
Molecular Weight: 342.43 g/mol
PubChem CID: 125672
CAS Number: 67727-97-3
Synonyms: MSH (11-13),  ACTH (11-13), alpha-MSH (11-13)

Source: PubChem