Format: 10 mg BPC-157 + 10 mg TB-500 (combined) · Purity: ≥99% by reverse-phase HPLC · Identity: ESI-MS confirmed
This blend pairs two of the most-studied repair peptides in one vial. BPC-157 is a stable gastric-derived pentadecapeptide, and TB-500 is a fragment of thymosin beta-4; both show up across tissue-repair research, and researchers often study them together to look at complementary repair pathways. Each vial holds 10 mg of each peptide, pre-combined.
Structure & Identity
This is a two-peptide blend rather than a single molecule, so each component keeps its own structure and identity. BPC-157 is a 15-amino-acid pentadecapeptide, Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, with a molecular weight of 1419.5 Da and CAS number 137525-51-0. TB-500 is synthetic thymosin beta-4, the full 43-residue acetylated peptide (Ac-SDKPTSFDKSKLKKTETQEKNPLPSKETIEQEKQAGES), with a molecular weight of 4963.55 Da and CAS number 77591-33-4; its actin-binding LKKTETQ region is the part responsible for the actin-regulating activity it is studied for. The two are combined at 10 mg each.
Research Background
The blend brings together two distinct repair-research threads.
- BPC-157 repair. BPC-157 is studied in tissue-repair and gastrointestinal models [PMID: 30915550].
- BPC-157 angiogenesis. Recent work examined its blood-vessel and nitric-oxide signaling [PMID: 41155565].
- TB-500 actin biology. Thymosin beta-4 is an actin-sequestering protein tied to cell migration [PMID: 16099219].
- TB-500 regeneration. It is described as a multifunctional regenerative peptide [PMID: 22074294].
- Complementary study. Pairing a gastric-derived repair peptide with an actin-regulating one covers more of the repair picture.
These are research contexts, not approved uses, and the blend is intended for laboratory study.
Specifications
| Attribute |
Value |
| Product type |
Blend (two peptides, combined) |
| Also Known As |
Wolverine Stack |
| Component 1 |
BPC-157, 10 mg (CAS 137525-51-0) |
| Component 2 |
TB-500 (thymosin beta-4 fragment), 10 mg (CAS 77591-33-4) |
| Total quantity |
20 mg per vial (10 mg + 10 mg) |
| Purity |
≥99% by reverse-phase HPLC (each component) |
| Identity |
Confirmed by ESI mass spectrometry |
| Physical form |
Lyophilized powder |
| Appearance |
White to off-white solid |
| Storage |
-20°C, protected from light |
| Solubility |
Soluble in bacteriostatic or sterile water |
| Classification |
Research use only |
Storage & Handling
Keep the sealed vial frozen at -20°C and shielded from light until use. After reconstitution, store the solution at 2-8°C and use it within about two weeks. Warm the vial to room temperature before opening to limit condensation, and avoid repeated freeze-thaw cycles so both peptides stay intact.
Storage and Handling Guide
Quality Assurance
The components of this blend are produced under research-grade manufacturing controls and verified by an independent lab before release. Purity is measured by reverse-phase HPLC and identity by mass spectrometry, with testing carried out by third-party laboratories, including Janoshik Analytical and domestic US labs. A certificate of analysis is published for each batch, so the results reflect the production lot you receive.
Quality & Testing
Frequently Asked Questions
What is the BPC-157 / TB-500 blend?
It is a combination research product with 10 mg each of BPC-157 (a gastric-derived pentadecapeptide) and TB-500 (a thymosin beta-4 fragment), pre-combined in one vial. It is studied in tissue-repair research and supplied for research use only.
Why are BPC-157 and TB-500 combined?
They are studied for complementary repair pathways, BPC-157 for gastric-derived repair signaling and TB-500 for actin-related cell migration, so pairing them lets researchers study both together.
Are the two peptides chemically joined?
No. They are two separate molecules combined in one vial, each keeping its own structure. This is a mixture, not a fused peptide.
How much of each peptide is in the vial?
There is 10 mg of BPC-157 and 10 mg of TB-500, for 20 mg of peptide total.
Is this blend FDA approved?
No. Neither component nor the blend is FDA approved. The material here is a research-use-only preparation, not for human or veterinary use.
Why is TB-500’s identity marked “confirm”?
Because “TB-500” is labelled differently across suppliers (fragment versus full protein), its exact identity and CAS should be verified against the actual material.
How should the blend be stored?
Keep the powder frozen at -20°C and protected from light. Once reconstituted for research, store at 2-8°C and use within about two weeks.
How are both components verified?
Each is tested to ≥99% purity by reverse-phase HPLC with mass-spec identity confirmation by an independent lab, and each batch has a published certificate of analysis.
References
- BPC 157: targeting angiogenesis and nitric oxide signaling. 2025. PMID: 41155565.
- Thymosin beta4: actin-sequestering protein moonlights to repair injured tissues. 2005. PMID: 16099219.
- Gastric pentadecapeptide BPC 157 and its role in accelerating healing. 2019. PMID: 30915550.
